twivHosts: Vincent RacanielloDick Despommier, and Alan Dove

Vincent, Dick, and Alan review a new macaque model for HIV-1 infection, a possible role for Epstein-Barr virus in multiple sclerosis, accidental release of H5N1 by a vaccine company, resistance of frogs to virus infection, and extreme virology – the biggest and smallest viruses and viral genomes.

Click the arrow above to play, or right-click to download TWiV #23 (34 MB .mp3,  49 minutes)

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Science blog of the week: H5N1 by Croft
Science podcast pick of the week: MicrobeWorld video
Science book of the week: Autism’s False Prophets by Paul A. Offit, MD (podcast with Dr. Ginger Campbell)

Send your virology questions and comments to twiv@microbe.tv.

Hosts: Vincent Racaniello and Chris Upton

Vincent and Chris Upton converse about hepatitis B in India, AIDS gene therapy with a ribozyme, antibodies that neutralize many influenza virus strains, killing tumors with vaccinia virus, myxoma virus of rabbits, and the Viral Bioinformatics Resource Center.

Click the arrow above to play, or right-click to download TWiV #22 (40 MB .mp3,  59 minutes)

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Science blog of the week: The VBRC blog by Chris Upton
Science podcast pick of the week: Nova ScienceNow
Science book of the week: The Hot Zone by Richard Preston

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Hosts: Vincent RacanielloDick Despommier, Alan Dove, and Max Gottesman

Vincent, Dick, Alan, and Max Gottesman discuss an unusual wasp-virus symbiosis, influenza transmission and absolute humidity, how mosquitoes survive Dengue virus infection, and viruses of bacteria.

Click the arrow above to play, or right-click to download TWiV #21 (38 MB .mp3,  55 minutes)

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  • Unusual wasp-virus symbiosis
  • Absolute humidity modulates influenza virus transmission, survival, and seasonality
  • How mosquitoes survive Dengue virus infection
  • Little Lambda, Who Made Thee?
  • Structure of HK97 procapsid

Science blog of the week: BioJobBlog by Cliff Mintz
Science podcast pick of the week: Distillations –  a weekly science podcast that brings you extracts from the past, present, and future of chemistry
Science book of the week: The Life of a Virus by Andrea Creager

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Hosts: Vincent Racaniello, Dick Despommier, Alan Dove, and Matt Evans

Vincent, Dick, Alan, and Matt Evans converse about TED, the Wakefield autism controversy, 99 rhinovirus sequences, Marburg in the USA, and hepatitis C virus.

Click the arrow above to play, or right-click to download TWiV #20 (46 MB .mp3, 66 minutes)

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  • A photographer catches Bill Gates’ mosquitoes
  • Joe DeRisi at TED
  • Dengue virus entry movie
  • Sequencing of 99 rhinovirus serotype genomes
  • Two views of the Wakefield autism controversy here and here
  • Marburg virus comes to the USA
  • Human occludin is a hepatitis C virus entry factor required for infection of mouse cells

Science blog of the week: Not exactly rocket science by Ed Yong
Science podcast pick of the week:
Neuropod
Science book of the week: Phage and the Origins of Molecular Biology Edited by John Cairns, Guther S. Stent, and James D. Watson

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Hosts: Vincent Racaniello and Alan Dove

Vincent and Alan discuss cap-snatching by the hantavirus N protein and the influenza virus endonuclease, HIV-1 and Ebola virus antagonism of tetherin, and influenza pneumonia.

Click the arrow above to play, or right-click to download TWiV #19 (28 MB .mp3, 40 minutes)

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Links for this episode:

Science blog of the week: Mystery Rays from Outer Space
Science podcast pick of the week: Emerging Infectious Diseases Podcast
Science book of the week: The Coming Plague by Laurie Garrett

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Hosts: Vincent Racaniello, Dick Despommier and Alan Dove

Vincent, Dick, and Alan discuss adenovirus type 36 and obesity, new influenza antiviral drugs, viral hemorrhagic septicemia virus of fish, and Ebola virus in pigs and pig farmers in the Phillipines.

Click the arrow above to play, or right-click to download TWiV #18 (35 MB .mp3, 50 minutes)

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Links for this episode:

Science blog of the week: Rubor Dolor Calor Tumor
Science podcast pick of the week: Originz
Science book of the week: Biohazard by Ken Alibek

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Hosts: Vincent Racaniello and Dick Despommier

Guest: Saul Silverstein

Vincent, Dick, and Saul talk about discoveries in virology that have had a major impact on the field.

Click the arrow above to play, or right-click to download TWiV #17 (37 MB .mp3,  57 minutes)

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  • Sem•i•nal (adjective): strongly influencing later developments.
  • Note: There are two HPV vaccines on the market: Gardasil (quadrivalent, types 6, 11, 16, 18) and Cervarix (bivalent, types 16 and 18).Gates Foundation donates to polio eradication effort.
  • Testing a bivalent oral poliovirus vaccine in India.
  • We played a clip from net@night episode 83.
  • I wrote about Jonathan Swift’s ‘Animalcules’ on virology blog.

Science blog of the week: Research Blogging
Science podcast pick of the week: Boston Museum of Science podcast
Science book of the weekThe Lives of a Cell: Notes of a Biology Watcher by Lewis Thomas

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Host: Vincent Racaniello

Guest: Jeremy Luban

Vincent and Jeremy, in Saanen, Switzerland, review the 19th Challenge in Virology meeting, and implications of a new HIV-1 sequence from 1960 for the origin of AIDS.

Click the arrow above to play, or right-click to download TWiV #16 (44 MB .mp3,  63 minutes)

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Links for this episode:

  • NY Times article on Offit vaccine book.
  • Nature paper on new 1960 HIV-1 sequence.
  • Massive polio immunization in Pakistan.
  • PLoS paper on T cell responses to HERVs in HIV-1 infection.

Science blog of the weekEye on DNA by Dr. Hsien-Hsien Lei
Science podcast pick of the weekPersiflager’s Infectious Disease Podcast
Science book of the weekMicrobe Hunters by by Paul de Kruif

TWiV is podcast of the week at net@night.

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Hosts: Vincent Racaniello, Dick Despommier, and Alan Dove

Vincent, Dick, and Alan converse about hantavirus spread by large deer mice, why the 1918 influenza virus replicates in the lower respiratory tract, measles in Europe, and the growing resistance of  influenza virus to antivirals.

Click the arrow above to play, or right-click to download TWiV #15 (37 MB .mp3,  53 minutes)

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Links for this episode:

Science blog of the week: Molecule of the Day
Science podcast pick of the week: Meet the Scientist by Merry Buckley
Science book of the weekThe Great Influenza by John M. Barry

The Origin of Species by Charles Darwin – published 150 years ago.

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Hosts: Vincent Racaniello and Alan Dove

Vincent and Alan discuss a viral upper respiratory tract infection, transmission of H5N1 influenza virus, death of an HIV denialist, and the Ebola outbreak in the Democratic Republic of the Congo.

Click the arrow above to play, or right-click to download TWiV #14 (37 MB .mp3, 53 minutes)

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Links for this episode:

  • PLoS Pathogens paper on transmission of H5N1 influenza virus.
  • Ebola outbreak in DRC reported by ProMedMail.
  • Death of HIV denialist.
  • BioCrowd, a network for bioscientists.
  • Molecules, the iPhone/iPod Touch app to display molecules.

Science blog of the week: ViroBlogy
Science podcast pick of the week: Astronomy Cast
Science book of the week: The Cutter Incident by Paul A. Offit, MD

Send your virology questions and comments to twiv@microbe.tv