Hap-1 cell karyotypeSean Whelan returns to TWiV to speak with Vincent about using haploid cell lines to identify genes encoding cell receptors for viruses, including Ebolavirus, Lassa virus, and more.

Host: Vincent Racaniello

Guest: Sean Whelan

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Download TWiV 486 (39 MB .mp3, 63 min)
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Intro music by Ronald Jenkees

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winefrontThe TWiV posse considers viral insulin-like peptides encoded in fish genomes, and insect antiviral immunity by production of viral DNA from defective genomes of RNA viruses.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Kathy Spindler, and Brianne Barker

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Download TWiV 485 (52 MB .mp3, 86 min)
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KathyVegas casinos lost money on physicists
BrianneAstronaut twin’s DNA is not 7% different!
DicksonParasitic Diseases lecture videos
AlanIn Season blog by Donna Long
Vincent – Buckyball viruses

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Paul – Wine labels (front, back)

Intro music is by Ronald Jenkees.

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tupanvirusThe TWiVumvirate discuss the giant Tupanvirus, with the longest tail in the known virosphere, and dampened STING dependent interferon activation in bats.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Kathy Spindler, and Brianne Barker

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Download TWiV 484 (53 MB .mp3, 87 min)
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KathyHow to read a phylogenetic tree
BrianneNo immune overload for vaccines
DicksonFlowchart of viral families
AlanLetters to a Pre-Scientist
Vincent – True believers, entrepreneurs, and scammers in alternative medicine and Simply Put: Vaccines Save Lives

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Vinayaka – Code of Ethics for Young Scientists
MattTWiV 443

Intro music is by Ronald Jenkees.

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deFonbrune chamberVincent and the Virals review undermining of antiviral effectiveness by genital inflammation, and heterogeneity of influenza virus infection in single cells.

Hosts: Vincent RacanielloAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 483 (61 MB .mp3, 101 min)
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KathyDance Dance
Rich – Snopes
AlanNext Generation Science Standards
Vincent – TWiEVO 28: Genetics of skin pigmentation in Africa

Intro music is by Ronald Jenkees.

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Aedes aegyptiThe TWiV Masters discuss serologic evidence of Ebolavirus infection in a population with no outbreaks, and the set of endogenous viral elements in the mosquito genome.

Hosts: Vincent Racaniello, Dickson DespommierAlan DoveKathy Spindler, and Brianne Barker

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Download TWiV 482 (59 MB .mp3, 98 min)
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KathyOrigami sound barrier
BrianneiBiology
DicksonSwitched-on bats
AlanHawaii’s communication breakdown
Vincent – Inside the Federal Bureau of way too many guns and What I Saw Treating Parkland Victims

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JohnyeDebunking Anti-Vaxxers

Intro music is by Ronald Jenkees.

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CoronavirusThe TWiVodrome considers the intestinal tract as an alternative infection route for MERS coronavirus, and how reduced accumulation of defective viral RNAs might lead to severe influenza.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 481 (62 MB .mp3, 102 min)
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KathyCD45.1 and CD45.2 mice may not be functionally equivalent
RichRelative humidity versus dewpoint (video)
DicksonUnderwater photography winners
AlanPhoto of a single atom
Vincent – Proposed Federal science budget cuts and The Blog is Dead

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JessLouis Tompkins Wright

Intro music is by Ronald Jenkees.

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Gesundheit-IIScott Hensley joins the TWiVites to review the current influenza season and presence of the virus in exhaled breath of symptomatic cases.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

Guest: Scott Hensley

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KathyFlow Virometry
RichFalcon Heavy Launch links:  Flight diagram; Launch including booster landing; Tesla in space; Tesla orbit; Reusable booster failures; Booster size
DicksonNext generation of weapons
AlanEd Yong’s story on fixing gender imbalance in science reporting
Vincent – CD4 Hunter iOS Android

Intro music is by Ronald Jenkees.

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Child with smallpoxThe TWiV team explains how infectious horsepox virus – likely the ancestor of smallpox vaccines – was recovered from chemically synthesized DNA fragments.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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KathyUM EEB photo contest
RichDino-Lite digital microscope and digital microscope camera
DicksonSandford Photography
AlanA list of female virologists
Vincent – Virology Lectures 2018

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AndrewInterferome
NevaThe Untreatable by Gavin Francis

Intro music is by Ronald Jenkees.

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Chemical synapseThe TWiVodrome explains how a gag-like protein from a retrotransposon forms virus-like particles that carry mRNA within vesicles across the synapse.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 477 (63 MB .mp3, 103 min)
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Send your virology questions and comments to twiv@microbe.tv