Calicivirus portal

The TWiV crew reveal a unique portal on the calcivirus capsid formed upon receptor engagement, and the regulation of interferon responses in virus-infected cells by methylation of mRNA.

Hosts: Vincent Racaniello, Dickson Despommier, Kathy Spindler, and Brianne Barker

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Download TWiV 534 (57 MB .mp3, 95 min)
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Weekly Science Picks 1:22:15

Brianne – The Red Queen’s Race Card Game
AlanPentax Papilio II
Dickson Felice Frankel on improving visual side of science
Kathy – History of the alphabet chart (free download) usefulcharts.com (see blog, such as Latin Greek Cyrillic Venn Diagram)
Vincent – Virology Lectures 2019

Listener Pick

Peter – Microbehunter (YouTube, blog, forum)

Intro music is by Ronald Jenkees.

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Rousettus

The TWiVosophers review the Chinese plasma virome revealed by non-invasive prenatal testing, and a new filovirus genome from bats in China.

Hosts: Vincent Racaniello, Rich ConditKathy Spindler, and Brianne Barker

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Download TWiV 533 (68 MB .mp3, 112 min)
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Weekly Science Picks 1:33:54

Brianne – Trying Polar Vortex Experiments at Home
Rich Three Identical Strangers
Kathy – Science wear, especially for Valentine’s Day (discount)
Vincent – State of anti-vaccine movement in US and Top 10 Health Threats for 2019

Listener Pick

AmyIf government can’t deliver safe vaccines, is it fit to rule?
Ted – Understanding Economics of Microbial Threats (pdf)

Intro music is by Ronald Jenkees.

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Wild boar

The TWiVers discuss the spread of African swine fever virus and its threat to pig farming, and the zoonotic potential of peste des petits ruminants virus.

Hosts: Vincent RacanielloAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 532 (60 MB .mp3, 99 min)
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Weekly Science Picks 1:25:27

Alan – Retraction Watch database
Rich “The Mayo Clinic: Faith Hope Science” by Ken Burns
Kathy – U-M EEB Photographer at Large contest
Vincent – Vaccines: An achievement of civilization

Listener Pick

DavidUseless Knowledge Begets New Horizons

Intro music is by Ronald Jenkees.

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circRNA

Patrick Moore returns to TWiV to discuss the discovery from the Chang-Moore laboratory of circular RNAs in cells infected with herpesviruses.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Kathy Spindler

Guest: Patrick Moore

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Download TWiV 531 (65 MB .mp3, 107 min)
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Weekly Science Picks 1:26:51

Brianne – The herd to the rescue
Alan – Magic Wings Butterfly Conservatory
Dickson100,000 Genomes Project
Kathy – Your Age on Other Worlds
Vincent – Vitamin D and Prevention of Cancer and Cardiovascular Disease
Pat (Dissenting)North Korea and Bioweapons

Listener Pick

EricThe Molecular Basis of Life

Intro music is by Ronald Jenkees.

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Retroviral silencingSteve Goff returns to TWiV to discuss the work of his laboratory on how retroviral genomes are silenced in infected cells.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Kathy Spindler

Guest: Steve Goff

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Download TWiV 530 (62 MB .mp3, 103 min)
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🎼 They’ll histone you when you start to transcribe,
And they’ll histone you just for tryin’ to get by,
So be careful when you uncoat your genome,
‘Cause everybody must histone.

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Weekly Science Picks 57:00, 1:27:39

Alan – The Tangled Tree by David Quammen
DicksonAmmonia could power the globe
Kathy – Portmanteaux and A.Word.A.Day
Vincent – Curioscity
SteveAlice and Bob Meet the Wall of Fire

Listener Pick

Chaim – Tony Fauci on getting your flu vaccine (mp3)

Intro music is by Ronald Jenkees.

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At the University of Wisconsin-Madison, Vincent meets up with one of his virology heroes, Roland R. Rueckert, to talk about his research and his second career as a forest manager.

Host: Vincent Racaniello

Guest: Roland R. Rueckert

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Download TWiV 529 (46 MB .mp3, 76 min)
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Intro music is by Ronald Jenkees.

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Starring virusIn the first episode for 2019, the TWiV team reviews the amazing virology stories of the past year.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 528 (77 MB .mp3, 128 min)
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Weekly Science Picks 1:39:10

Alan – Pandemic Trail game
RichOn a Bat’s Wing and a Prayer
Dickson – Decoding Watson
KathyPhenotypic variation in outbred and inbred mice
Vincent – Trump County Confronts the Administration Amid Rash of Child Cancers

Listener Pick

AnnePeter Hotez interview
Islam – Letter from Crick to Watson (pdf)

Intro music is by Ronald Jenkees.

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Four Corners USAThe TWiV team summarizes the discovery of Sin Nombre virus, and presents evidence that neurotropic flaviviruses can cause intestinal dysmotility syndromes after systemic infection of mice.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 527 (53 MB .mp3, 87 min)
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Weekly Science Picks 1:09:58

Alan – Zooming in to Sagittarius A, ESO video
RichOrbits and Ice Ages: A History of Climate
DicksonNational Geographic Best Photos 2018
Kathy – HealthMap Vaccine Finder
Vincent – Taylor Custom

Listener Pick

NealThe Yoda of Silicon Valley

Intro music is by Ronald Jenkees.

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RNA virus evolutionThe TWiV hosts discuss the distribution of prions in the eyes of patients with sporadic Creutzfeldt-Jacob disease, and the origins and evolution of RNA viruses.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 526 (63 MB .mp3, 104 min)
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Weekly Science Picks 1:32:39

Alan – Population mountains to visualize cities
RichA Neanderthal Perspective on Human Origins with Svante Pääbo
Kathy – NASA Space Mission posters
Vincent – Package Thief vs Glitter Bomb Trap

Listener Pick

NealWas a Scientist Jailed?

Intro music is by Ronald Jenkees.

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Peter HotezVaccine scientist, pediatrician, and autism dad Peter Hotez talks about his new book, Vaccines Did Not Cause Rachel’s Autism.

Host: Vincent Racaniello

Guest: Peter Hotez

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Download TWiV Special (12 MB .mp3, 19 min)
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Links for this episode

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv