tupanvirusThe TWiVumvirate discuss the giant Tupanvirus, with the longest tail in the known virosphere, and dampened STING dependent interferon activation in bats.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Kathy Spindler, and Brianne Barker

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Download TWiV 484 (53 MB .mp3, 87 min)
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KathyHow to read a phylogenetic tree
BrianneNo immune overload for vaccines
DicksonFlowchart of viral families
AlanLetters to a Pre-Scientist
Vincent – True believers, entrepreneurs, and scammers in alternative medicine and Simply Put: Vaccines Save Lives

Listener Picks

Vinayaka – Code of Ethics for Young Scientists
MattTWiV 443

Intro music is by Ronald Jenkees.

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deFonbrune chamberVincent and the Virals review undermining of antiviral effectiveness by genital inflammation, and heterogeneity of influenza virus infection in single cells.

Hosts: Vincent RacanielloAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 483 (61 MB .mp3, 101 min)
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KathyDance Dance
Rich – Snopes
AlanNext Generation Science Standards
Vincent – TWiEVO 28: Genetics of skin pigmentation in Africa

Intro music is by Ronald Jenkees.

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Aedes aegyptiThe TWiV Masters discuss serologic evidence of Ebolavirus infection in a population with no outbreaks, and the set of endogenous viral elements in the mosquito genome.

Hosts: Vincent Racaniello, Dickson DespommierAlan DoveKathy Spindler, and Brianne Barker

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Download TWiV 482 (59 MB .mp3, 98 min)
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KathyOrigami sound barrier
BrianneiBiology
DicksonSwitched-on bats
AlanHawaii’s communication breakdown
Vincent – Inside the Federal Bureau of way too many guns and What I Saw Treating Parkland Victims

Listener Pick

JohnyeDebunking Anti-Vaxxers

Intro music is by Ronald Jenkees.

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CoronavirusThe TWiVodrome considers the intestinal tract as an alternative infection route for MERS coronavirus, and how reduced accumulation of defective viral RNAs might lead to severe influenza.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 481 (62 MB .mp3, 102 min)
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KathyCD45.1 and CD45.2 mice may not be functionally equivalent
RichRelative humidity versus dewpoint (video)
DicksonUnderwater photography winners
AlanPhoto of a single atom
Vincent – Proposed Federal science budget cuts and The Blog is Dead

Listener Pick

JessLouis Tompkins Wright

Intro music is by Ronald Jenkees.

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Gesundheit-IIScott Hensley joins the TWiVites to review the current influenza season and presence of the virus in exhaled breath of symptomatic cases.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

Guest: Scott Hensley

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KathyFlow Virometry
RichFalcon Heavy Launch links:  Flight diagram; Launch including booster landing; Tesla in space; Tesla orbit; Reusable booster failures; Booster size
DicksonNext generation of weapons
AlanEd Yong’s story on fixing gender imbalance in science reporting
Vincent – CD4 Hunter iOS Android

Intro music is by Ronald Jenkees.

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Child with smallpoxThe TWiV team explains how infectious horsepox virus – likely the ancestor of smallpox vaccines – was recovered from chemically synthesized DNA fragments.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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KathyUM EEB photo contest
RichDino-Lite digital microscope and digital microscope camera
DicksonSandford Photography
AlanA list of female virologists
Vincent – Virology Lectures 2018

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AndrewInterferome
NevaThe Untreatable by Gavin Francis

Intro music is by Ronald Jenkees.

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Chemical synapseThe TWiVodrome explains how a gag-like protein from a retrotransposon forms virus-like particles that carry mRNA within vesicles across the synapse.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

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Download TWiV 477 (63 MB .mp3, 103 min)
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Malate-Aspartate shuttle

Malate-Aspartate shuttle

Nels joins the TWiV team to talk about his work on genomic accordions in vaccinia virus, hepatitis B virus in a 439 year old mummy, and viral induction of energy synthesis by a long noncoding RNA.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, Rich Condit, and Kathy Spindler

Guest: Nels Elde

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The Legos of TWiV

The TWiV Team. From left to right: Vincent, Dickson, Alan, Rich, Kathy.

In the first episode for 2018, the TWiV team reviews the amazing virology stories of 2017.

Hosts: Vincent Racaniello, Dickson DespommierAlan Dove, and Kathy Spindler

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Download TWiV 475 (67 MB .mp3, 110 min)
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KathyVoyager recording and book
Rich – David Sheldrick Wildlife Trust (Maktao)
DicksonGlobal Croplands Map
AlanThe Great Influenza one day at a time
Vincent – The Doomsday Machine by Daniel Ellsberg

Listener Picks

MarkScience Moms
Brian – Science of HIV
Andy – Ask Me Anything
SteveCritical Attitude in Medicine

Intro music is by Ronald Jenkees.

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