The Masters of the ScienTWIVic Universe discuss a novel poxvirus isolate from an immunosuppressed patient, H1N1 and the gain-of-function debate, and attenuation of dengue virus by recoding the genome.

Colin writes: Dear TWiV hosts, I have recently become addicted to your podcasts. I’ve had an interest in infectious diseases for a long time, but without much of a background in microbiology or virology, I…

The un-encapsidated TWiV Humans discuss finding hepatitis D virus-related sequences in birds and snakes, and fatal swine acute diarrhoea syndrome caused by a coronavirus of bat origin.

Henry writes: Dear Dr. Vincent and everyone involved in this great space for the dissemination of science. There are no words to describe how happy I was when I heard that our new paper describing…

Seth Carus writes: Dear Dr. Racaniello and colleagues, I enjoyed your conversation with Jens Kuhn. His comments on the complexity of creating biological weapons were right on the mark and serve as a useful counterpoint…

The TWiVniks explain how the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city by release of mosquitoes harboring Wolbachia.

David writes: Dear Twivniks, Re TWiV 505, here’s a thought on potential mechanisms for involvement of virus immunity in Alzheimer’s disease. I’m sure I read somewhere the notion that the capacity of cells to dispose…