Lonya and Jeremy take the TWiV team beTWIXt primate immunodeficiency virus proteins Vpx and Vpr and how they counteract transcriptional repression of proviruses by the HUSH complex.
Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Kathy Spindler, and Brianne Barker
Guests: Leonid Yorkovetskiy and Jeremy Luban
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Download TWiV 516 (73 MB .mp3, 121 min)
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Links for this episode
- Pan American Society for Clinical Virology San Diego and Houston Regional Meetings 4:22
- Vpr and Vpx counter HUSH (Nat Micro) 8:34, 56:46
- Vpr and Vpx counter HUSH (bioRxiv version)
- Schematic of HUSH complex (Lehner lab) 1:08:17
- Olive colobus monkey sound credit 1:53:14
- Image credit: William (Ted) Diehl
- Letters read on TWiV 516 5:07
- Timestamps by Jolene. Thanks!
Weekly Science Picks 1:44:39
Brianne – The Chimp and the River by David Quammen
Rich – James Cook’s First Voyage Journal (20 sec Google Earth summary)
Kathy – High resolution Antarctica map NYTimes 46MB Maps (more info and 43 tb maps)
Dickson – Jellyfish
Jeremy – Pictorial Guide to Living Primates; All The World’s Primates
Lonya – Chougui et al. HIV-2/SIV Vpx counters HUSH
Vincent – Research!America
Intro music is by Ronald Jenkees.
Send your virology questions and comments to twiv@microbe.tv
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