TWiV 573: Inventing viruses

Bill Summers

William Summers joins the TWiV team to discuss some virology history, including the ever-changing concept of ‘virus’ and the contribution of phage research to the study of animal viruses.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Rich Condit

Guest: William Summers

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Weekly Science Picks 1:34:36

Alan – Restoration of Western Flyer
Rich – Purification of phage T7 RNA polymerase
Dickson – The Galaxy is Not Flat
Bill – Efficacy of tetravalent dengue vaccine
Vincent – Blowout by Rachel Maddow

Intro music is by Ronald Jenkees.

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TWiV 572: Your EV-D68th nervous breakdown

Enterovirus D68

Amy joins the TWiV team to review evidence that enterovirus D68 is an etiologic agent of childhood paralysis, and her finding that the ability of the virus to infect cells of the nervous system is not a recently acquired property.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler

Guest: Amy Rosenfeld

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Weekly Science Picks 1:39:49


Amy – Enterovirus biology and pathogenesis and Acute Flaccid Myelitis Association
Rich – Tesla
Dickson – Nikon Small World 2019 Photo Competition
Kathy – Term limits in academic leadership #1 and #2
Vincent – Coywolf: New hybrid carnivore

Listener Picks

Anonymous – Spill the Beans vaccinated shirts

Intro music is by Ronald Jenkees.

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TWiV 571: Piwi koalas

The League of Extraordinary Virologists celebrate the eradication of wild poliovirus type 3, and consider the effectiveness of an influenza vaccine produced in insect cells, and how small RNAs are protecting the Koala germline from retroviral invasion.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker

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Weekly Science Picks 1:29:29

Brianne – The Machinery of Life by David Goodsell
Alan – Pomological watercolors
Dickson – Wildlife Photographer of the Year
Kathy – DiversifyMicrobiology  DiversifyImmunology and Marmot becomes fox food
Vincent – Burnet A Life by Christopher Sexton

Listener Picks

Justin – Worm with three sexes
M

Intro music is by Ronald Jenkees.

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TWiV 570: Aarhus viral

At Aarhus University in Denmark, Vincent speaks with Trine Mogensen, Søren Paludan, Ole Søgaard, and Madalina Carter-Timofte about their careers and their work on sensing herpesviral DNA, immunodeficiencies that predispose to severe viral infections, and the path to a cure for HIV/AIDS.

Hosts: Vincent Racaniello

Guests: Trine Mogensen, Søren Paludan, Ole Søgaard, and Madalina Carter-Timofte

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Intro music is by Ronald Jenkees.

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TWiV 569: Smolt’in iron

Aedes aegypti

The TWiV pro-vaxxers reveal viruses that infect endangered wild salmon, and how iron in host serum modulates dengue virus acquisition by mosquitoes.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Brianne Barker

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Weekly Science Picks 1:21:14

Brianne – Retraction of new CCR5/lifespan study
Alan – Nomad Press illustrated science books, and illustrator Lex Cornell
Dickson – RARE: Creatures of the Photo Ark
Vincent – The Odyssey of Eradication by Thomas Abraham

Listener Picks

Justin – Mass spec pen
Mark – What really brought down the Boeing 737 Max?

Intro music is by Ronald Jenkees.

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TWiV 568: Karolinska viral

In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation.

Hosts: Vincent Racaniello

Guests: Jan Albert, Petter Brodin, and Anna Smed-Sörensen

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Download TWiV 568 (58 MB .mp3, 95 min)
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Intro music is by Ronald Jenkees.

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TWiV 567: Outbreaks and a breakout

The TWiV team covers outbreaks of eastern equine encephalitis virus in the US and poliovirus in the Philippines, and explain how a chemokine induced by HIV-1 infection helps release more virus particles from cells.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, Kathy Spindler, and Brianne Barker

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Weekly Science Picks 1:34:44

Brianne – History of infectious disease before/after vaccines
Alan – NIH Ham Radio Club
Rich – Renewable jet fuel from air
Dickson – Newly Discovered Comet Is Likely Interstellar Visitor
Kathy – How professors spend their time
Vincent – Non-polio enterovirus surveillance network

Listener Picks

Alexey – Periodic Table Podcasts and Videos

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 566: Chicken gumbo and a corona

The TWiV team reveals the protein corona that surrounds virus particles and influences infectivity and amyloid aggregation, and a proofreading-impaired herpesvirus that produces quasispecies-like populations.

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit

Guest: Kiki Warren

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Weekly Science Picks 1:29:39

Alan – Astronomy photographer of the year
Rich – Urban living leads to high cholesterol… in crows
Kiki – Reversal of epigenetic aging
Vincent – General Virology by SE Luria

Listener Picks

Sindhu – Sweden Solar System
Anthony – Surprising role of viruses in evolution with Eugene Koonin
Paul – The Obscure Virus Club

Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

TWiV 565: Karolinska virology

From the Karolinska Institute in Stockholm, Vincent speaks with Niklas Björkström, Ali Mirazimi, and Matti Sällberg about their work on the impact of chronic hepatitis C virus infection on NK cells, Crimean-Congo hemorrhagic fever virus vaccines, and immunotherapy to block entry of hepatitis B and D viruses.

Hosts: Vincent Racaniello

Guests: Niklas Björkström, Ali Mirazimi, and Matti Sällberg

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Download TWiV 565 (52 MB .mp3, 86 min)
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Intro music is by Ronald Jenkees.

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TWiV 564: Virology Nobel Prizes with Erling Norrby

From the 16th Smögen Summer Symposium on Virology, Vincent speaks with Erling Norrby about how he has used archival material to provide insight into early Nobel Prizes for research on viruses.

Hosts: Vincent Racaniello

Guest: Erling Norrby

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Download TWiV 564 (45 MB .mp3, 74 min)
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Intro music is by Ronald Jenkees.

Send your virology questions and comments to twiv@microbe.tv

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