brugia_malayiHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson review an in silico pipeline for identifying molecular mimicry candidate proteins in the genomes of parasites, and catch up on listener email.

Download TWiP #33 (63 MB .mp3, 88 minutes).

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tcruzi_nfkbHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss immune evasion by the cruzain protease of T. cruzi, and novel tetraspanin antigens of S. japonicum.

Download TWiP #32 (65 MB .mp3, 90 minutes).

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weissbrod_p.falciparum_life_cycleHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss the promising results of a phase III trial of a malaria vaccine in African children

Download TWiP #31 (50 MB .mp3, 70 minutes).

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knirschcharlesHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson have a broad-ranging conversation with Charles Knirsch of Pfizer, Inc. about how public-private partnerships can function to control and eliminate infectious diseases.

Download TWiP #30 (61 MB .mp3, 85 minutes).

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hotez_clintonHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson converse with Peter Hotez about global health, vaccinology, and neglected tropical diseases.

Download TWiP #29 (47 MB .mp3, 65 minutes)

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anopheles_gambiaeHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss medical entomology with Robert W. Gwadz, Assistant Chief of the Laboratory of Malaria and Vector Research at NIAID.

Download TWiP #28 (65 MB .mp3, 91 minutes)

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clonorchis_adultHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson continue their discussion of trematodes, or flukes, which have a snail as a reservoir host.

Download TWiP #27 (56 MB .mp3, 77 minutes)

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s_mansoni_adult_semHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson take on the schistosomes, agents of a series of related diseases in humans referred to as schistosomiasis.

Download TWiP #26 (68 MB .mp3, 95 minutes)

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wuchereria_microfilariaHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson review Wuchereria bancrofti, the nematode that causes lymphatic filariasis, also known as elephantiasis.

Download TWiP #25 (32 MB .mp3, 67 minutes)

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onchocerca_microfilariaHosts: Vincent Racaniello and Dickson Despommier

Vincent and Dickson discuss the life cycle and pathogenesis of Onchocerca volvulus, the vector-borne filarial nematode parasite that causes onchocerciasis, or river blindness

Download TWiP #24 (59 MB .mp3, 82 minutes)

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