microbial sibling conflictThe TWiM team discuss bacteriophage evolution in a dairy plant, and killing of less fit cells among social microbes.

Hosts: Vincent RacanielloMichael SchmidtElio Schaechter and Michele Swanson

Right click to download TWiM#177 (26 MB .mp3, 55 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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old wormVincent, Michael and Elio note the passing of Stanley Falkow, give E. coli an archaeal membrane, and show how the microbiome can make worms live longer.

Hosts: Vincent RacanielloMichael Schmidt, and Elio Schaechter

Right click to download TWiM#176 (29 MB .mp3, 60 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Neomycin

Neomycins

The TWiM team notes the passing of Allan Campbell, and explains how aminoglycoside antibiotics like neomycin enhance host resistance to viral infection.

Hosts: Vincent RacanielloMichael Schmidt, and Michele Swanson

Right click to download TWiM#175 (30 MB .mp3, 63 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Mary MallonThe TWiMsters explain why untreatable typhoid fever might be on the way, and the evolution of fungal virulence in tropical frogs.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Right click to download TWiM#174 (30 MB .mp3, 62 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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ElioThe Masters of the Microbiological Universe discuss the humongouest fungus, and a commensal bacterium that protects against skin neoplasia.

Hosts: Vincent Racaniello, Elio SchaechterMichael Schmidt, and Michele Swanson

Right click to download TWiM#173 (35 MB .mp3, 74 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Approvals of antibacterials

Number of antibacterial new drug application (NDA) approvals vs year intervals. Drugs limited to systemic agents.

The TWiMmers discuss culture-independent discovery of malacidin antibiotics, and unfolding of relaxase during bacterial conjugation.

Hosts: Vincent Racaniello, Elio SchaechterMichael Schmidt, and Michele Swanson

Right click to download TWiM#172 (35 MB .mp3, 74 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Stingless bee

The stingless bee Scaptotrigona depilis

The TWiM team explores a stingless bee that requires a fungal steroid to pupate, and colonic biofilms containing tumorigenic bacteria in patients with colorectal polyps.

Hosts: Vincent Racaniello, Elio Schaechter, and Michael Schmidt

Right click to download TWiM#171 (29 MB .mp3, 61 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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influenza protein nanoparticleThe TWiM team reveals that spread of plague was likely by human ectoparasites, not rats, and deconstruct a durable, broadly protective protein nanoparticle influenza virus vaccine.

Host: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson

Right click to download TWiM#170 (27 MB .mp3, 56 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Robinson Ridge

Robinson Ridge, Antarctica, looking towards Sparkes Bay.

The cast of TWiM reveals how uropathogenic E. coli use a binding protein to treat copper as a nutrient or a toxin, and Antarctic soil bacteria that survive on trace atmospheric gases.

Host: Vincent Racaniello, Michael Schmidt, Elio Schaechter, and Michele Swanson

Right click to download TWiM#169 (37 MB .mp3, 77 minutes)

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Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

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Maize weevilDickson joins the TWiM team to discuss the nasal microbiota of dairy farmers, and attenuation of bacterial virulence by quorum sensing in the maize weevil.

Host: Vincent Racaniello, Michael Schmidt, and Michele Swanson

Guest: Dickson Despommier

Right click to download TWiM#168 (37 MB .mp3, 77 minutes)

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Links for this episode

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv