The Immune trifecta explores systems immunology, and its use in a study of immune system development in newborn children.
Cindy and Vincent describe the construction of a gene network that programs mammalian cells to detect and eliminate bacterial infections.
The Immune team travels to the University of Maryland for ASV 2018, where they meet up with Rebecca Lynch to explore her work on broadly neutralizing antibodies against HIV-1.
The Immune team explores the variable lymphocyte receptors of jawless vertebrates, a system of immunity that parallels the structurally unrelated antibodies of jawed vertebrates.
The Immune team reveals how γδT cells that synthesize interleukin-17A regulate adipose regulatory T cell homeostasis and thermogenesis.
The Immune hosts discuss how the complement system functions, and its role in early synapse loss in a mouse model of Alzheimer’s disease.
The Immune hosts explain how antibody molecules mature, then discuss the finding in infants of potent neutralizing antibodies against respiratory syncytial virus without somatic hypermutation.
The ImmuoModulators provide a primer on mucosal defenses, and explain how sensitizing female mice to food allergens prevents allergic reactions in their offspring.
The immu-knowledge-ists deconstruct the holy grail of oncologists, cancer immunotherapy, and the exciting development of CAR T cells and how they work.
Cindy, Steph, and Vincent discuss recent problems with dengue virus vaccine, and a bi-specific monoclonal antibody against Zika virus.