Immune explains a study of 125 COVID-19 patients by deep immune profiling, which revealed three immunotypes associated with poor clinical prognosis or recovery.

Hosts: Vincent Racaniello and Cynthia Leifer

Guest: Brianne Barker

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Music by Steve Neal.
Immune logo image by Blausen Medical

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Immune continues a discussion of the immune response to infection with SARS-CoV-2, including inflammatory responses and disease, antibody and T-cell responses, and vaccines, and answers to listener questions.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

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Music by Steve Neal. Immune logo image by Blausen Medical

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Immune continues a discussion of the immune response to infection with SARS-CoV-2, including vaccines and immunity, effects of BCG and OPV, immunity passports, and answers to listener questions.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

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Music by Steve Neal. Immune logo image by Blausen Medical.

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Brianne Barker returns to continue a discussion of the immune response to infection with SARS-CoV-2, including use of steroid, coagulation in some patients, cytokine storm, and vaccines.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

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Download Immune 30 (51 MB .mp3, 83 min)
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Music by Steve Neal. Immune logo image by Blausen Medical.

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Brianne Barker joins Immune to discuss the immune response to infection with SARS-CoV-2, including immune respones, pathogenesis, immunopathology and more.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Brianne Barker

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Download Immune 29 (53 MB .mp3, 87 min)
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Music by Steve Neal. Immune logo image by Blausen Medical.

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Irene Salinas joins Immune to reveal the work of her laboratory on the evolution of mucosal immune responses in teleost fish, the oldest living bony vertebrates.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Irene Salinas

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Music by Steve Neal. Immune logo image by Blausen Medical.

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Steph explains how sepsis induces protective immune memory in NK cells, via histone methylation of the interferon gamma enhancer.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:22:07

Steph – Rotavirus & polio vaccines should be separated (article, paper)
CindyDiversify Immunology
VincentNo winter break from publish or perish

Music by Steve Neal. Immune logo image by Blausen Medical.

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measles virus

Michael Mina joins the Immune team to explain his findings that measles diminishes pre-existing antibodies that protect against infection with other pathogens.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

Guest: Michael Mina

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Download Immune 26 (59 MB .mp3, 98 min)
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Music by Steve Neal. Immune logo image by Blausen Medical.

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The Immune team explains that short chain fatty acids produced by microbial fermentation of fiber rewire metabolism to enable the production of memory T cells.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:09:20

Stephanie – This Week in Neuroscience
CindyGraduate Abuse by Derek Lowe
VincentFunding ends for seeking new viruses

Music by Steve Neal. Immune logo image by Blausen Medical.

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The Immune team reveals a new type of T helper cell that drives the production of IgE, leading to allergic responses.

Mast cells

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:22:54

CindyLasker Award 2019
VincentEleanor’s Breakthrough video

Music by Steve Neal. Immune logo image by Blausen Medical.

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