The immunosomes explain that widely used inbred laboratory mice are not identical, and how to tell them apart.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:19:10

StephUniversity of Alaska budget crisis
Cindy90% survival following new Ebolavirus treatments
Vincent Immunology videos at Blausen Medical

Music by Steve Neal. Immune logo image by Blausen Medical.

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Immune reveals an alternative to a protective vaccine, engineered B cells that produce antiviral antibodies.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:07:59

StephBreath of fresh air
CindyBiologist found dead
VincentNobel Prizes and Nature’s Surprises by Erling Norrby

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Immune tackles the finding that patients with Type I diabetes have lymphocytes with both TCR and BCR that may drive the pathogenesis of the disease.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:18:43

StephUnique Scientists
CindyResearcher app
VincentSTLR Conversations Podcast

Music by Steve Neal. Immune logo image by Blausen Medical.

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The Immune trio explains how activation of the inflammasome by a bacterial protein causes blood clotting through a programmed cell death process called pyroptosis.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:13:56

StephiBiology Immunology Course
CindyChanging vaccine hesitancy
VincentBad Advice by Paul Offit (and Vaccines and Your Child)

Listener Pick

SteveAn Elegant Defense

Music by Steve Neal. Immune logo image by Blausen Medical.

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The Immune team discusses immunization of pregnant mice to protect offspring from neonatal herpes simplex virus disease.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:10:05

StephiNaturalist
CindyTaking a break is also hard work
VincentImmunology Wall Posters

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trogocytosis

The immunophiles discuss T cell antigen discovery by trogocytosis – the transfer of membrane patches among cells in close contact.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:07:15

StephScientists rise up against statistical significance
CindyWhy I quit my PhD and returned
VincentThe Law and Vaccine Resistance

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The immunophiles explain how metabolic rewiring of macrophages by CpG promotes clearance of cancer cells.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:01:30

StephPregnant Scholar
CindyAnti-vaxxers vaccinating against measles
VincentCenter for Science in the Public Interest

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The Immune team turns to chickens, which have been important in understanding the immune system, to show that infection of mature B cells is not required for the pathogenesis of Marek’s disease herpesvirus.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:01:20

Steph7 Days Out
Cindy – Watson PBS documentary and Cold Spring Harbor Laboratory response
VincentDads can donate mitochondrial DNA and Chicken puns

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neutrophilStephanie takes the Immune team on a tour of neutrophils, the most abundant leukocytes in mammals, including tethers and slings, neutrophil rolling, and neutrophil nets.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:14:01

Steph – Should reviewers remain anonymous?
CindyBreast Cancer Research Foundation
VincentInitiative to End Paywalls (The Scientist)

Listener Pick

Jim – Eat to Live (YouTube)

Music by Steve Neal. Immune logo image by Blausen Medical.

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Immune checkpoint inhibitorThe Immune team explains the science behind the 2018 Nobel Prizes awarded to Allison and Honjo: checkpoint immunotherapy.

Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer

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Weekly Science Picks 1:13:25

StephImmunobites
CindyList of immunology Nobels
VincentProf. Barker’s Immunology lectures

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