BacterioFiles 362: Combining Chromosomes

November 19, 2018

This episode: Combining all 16 of yeast’s chromosomes into one or two only impairs their growth slightly in the lab, but it prevents them from successful mating with wild yeasts!

Download Episode (12 MB, 14 minutes)

Show notes:
Microbe of the episode: Vibrio succinogenes

News item 1/News item 2

Journal Papers:
Luo J, Sun X, Cormack BP, Boeke JD. 2018. Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast. Nature 560:392–396.
Shao Y, Lu N, Wu Z, Cai C, Wang S, Zhang L-L, Zhou F, Xiao S, Liu L, Zeng X, Zheng H, Yang C, Zhao Z, Zhao G, Zhou J-Q, Xue X, Qin Z. 2018. Creating a functional single-chromosome yeast. Nature 560:331–335.

Other interesting stories:

Post questions or comments here or email to Thanks for listening!

Subscribe at iTunes or Google Play, support the show at Patreon, or check out the show at Twitter, or Facebook

Leave a Reply

Your email address will not be published. Required fields are marked *

Content on this site is licensed by Microbe TV, LLC under a Creative Commons Attribution 3.0 License