This episode: Bacteriophages with defenses against bacterial CRISPR defenses have to work together to succeed!
Thanks to Drs. Edze Westra and Stineke van Houte for their contributions, and to Calvin Cornell for suggesting this story!
Download Episode (10 MB, 11 minutes)
Microbe of the episode: Lactobacillus casei subsp. alactosus
Borges AL, Zhang JY, Rollins MF, Osuna BA, Wiedenheft B, Bondy-Denomy J. 2018. Bacteriophage Cooperation Suppresses CRISPR-Cas3 and Cas9 Immunity. Cell 174:917-925.e10.
Landsberger M, Gandon S, Meaden S, Rollie C, Chevallereau A, Chabas H, Buckling A, Westra ER, Houte S van. 2018. Anti-CRISPR Phages Cooperate to Overcome CRISPR-Cas Immunity. Cell 174:908-916.e12.
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