BacterioFiles 282: Mycobacteria Make Mice Mellow

January 16, 2017

Elevated plus-maze
By Bd008 – Own work
CC BY-SA 3.0

This episode: Vaccinating mice with heat-killed soil bacteria reduced their stressed behavior and inflammation!

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Show notes:

Journal Paper:
Reber SO, Siebler PH, Donner NC, Morton JT, Smith DG, Kopelman JM, Lowe KR, Wheeler KJ, Fox JH, Hassell JE, Greenwood BN, Jansch C, Lechner A, Schmidt D, Uschold-Schmidt N, Füchsl AM, Langgartner D, Walker FR, Hale MW, Perez GL, Treuren WV, González A, Halweg-Edwards AL, Fleshner M, Raison CL, Rook GA, Peddada SD, Knight R, Lowry CA. 2016. Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice. Proc Natl Acad Sci 113:E3130–E3139.

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